|
KMID : 0370220150590050222
|
|
Yakhak Hoeji
2015 Volume.59 No. 5 p.222 ~ p.229
|
|
|
Isolation of Constituents of Lihtospermum erythrorhizon and Development of an Analytical Method of its Constituents by HPLC-UV
|
|
홍은영:Hong Eun-Young
경민지:Kyung Min-Ji/황완균:Whang Wan-Kyunn
|
|
|
Abstract
|
|
|
Lithospermi radix, the dried roots of Litospermum erythrorhizon Sieboid et Zuccarini (Boraginaceae), has long been used to treat detoxification and inflammation. In this study, we isolated two main quinoid compounds, β-droxyisovalerylshikonin
(1) and acetylshikonin (2) from L. erythrorhizon. As acetylshikonin is considered as a marker compound of L. erythrorhizon, a rapid analysis method for the simultaneous determination of quinoid compounds including 2 was also developed by HPLC (High Performance Liquid Chromatography) and validation of this analytical method. By the developed
method, two quinoid marker compounds (β-hydroxyisovalerylshikonin and acetylshikonin) were successfully quantified in
31 commercial samples which were collected from different regions. The contents were 0.20% (β- hydroxyisovalerylshikonin) and 0.22% (acetylshikonin), respectively.
|
|
|
KEYWORD
|
|
|
Lithospermi radix, acetylshikonin, β-hydroxyisovalerylshikonin, HPLC
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|